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Table 4 Univariate and multivariable COX regression analyses

From: Short- and Long-term survival prediction in patients with acute type A aortic dissection undergoing open surgery

Variables

Univariate

HR (95% CI)

P

Multivariate

HR (95% CI)

P

Age ≥ 58(y)

2.350(1.29–3.865)

0.001

2.659(1.584–4.462)

< 0.001

Cardiac surgery history

2.944(1.070–8.097)

0.036

4.242(1.411–12.756)

0.010

MFS

3.801(0.929–15.552)

0.063

12.042(2.597–55.831)

0.001

Nephritis

4.62(2.205–9.029)

< 0.001

4.917(2.349–10.293)

< 0.001

Preoperative CRRT

16.147(2.181–119.564)

0.006

  

WBC ≥ 10.45(× 10*9/L)

2.471(1.369–4.458)

0.003

2.451(1.304–4.607)

0.005

ALT ≥ 33.5(U/L)

2.552(1.545–4.125)

< 0.001

  

TBIL (umol/L)

1.024(1.010–1.037)

< 0.001

1.021(1.007–1.035)

0.003

CR ≥ 104(umol/L)

3.562(2.190–5.795)

< 0.001

  

Phosphorus ≥ 1.4(mmol/L)

2.918(1.766–4.819)

< 0.001

2.705(1.584–4.621)

< 0.001

Fibrinogen

0.748(0.601–0.930)

0.0009

  

D-dimer ≥ 4.4(mg/L)

4.183(2.071–8.450)

< 0.001

3.084(1.498–6.35)

0.002

NLR ≥ 7.1

2.716(1.297–5.689)

0.008

  

MLR ≥ 0.66

1.827(1.063–3.140)

0.029

  

PLR ≥ 118

0.761(0.453–1.277)

0.301

  

SII ≥ 1391

1.662(0.905–3.053)

0.101

  

Dimer/l ≥ 5.56

3.008(1.609–5.622)

 < 0.001

  

SCI ≥ 34

0.406(0.225–0.733)

0.003

  

False lumen type

1.322(0.952–1.835)

0.096

  

Single tear

1.765(1.154–2.699)

0.009

  

Multiple tears

0.339(0.136–0.843)

0.020

0.369(0.145–0.939)

0.036

EoI in AD

1.033(0.944–1.130)

0.483

  

IB in AD

0.894(0.778–1.026)

0.111

  

Involvement of iliac arteries

0.981(0.559–1.722)

0.946

  

MA in AD

1.863(0.975–3.56)

0.060

  

RA in AD

1.394(0.665–2.919)

0.379

  

FLM SS

1.170(0.559–2.451)

0.677

  

FLM CS

0.754(0.430–1.325)

0.327

  

Pericardial effusion

2.006(0.916–4.391)

0.082

  

Pleural effusion

0.612(0.264–1.416)

0.251

  

Associated aneurysms

1.087(0.619–1.909)

0.772

  

True cavity

0.906(0.715–1.149)

0.416

  

Ascending aortic diameter

1.231(0.952–1.591)

0.112

  

True cavity total diameter ratio

0.655(0.211–2.036)

0.465

  

False cavity

1.126(0.933–1.358)

0.217

  

True to false cavity ratio

0.932(0.835–1.040)

0.207

  
  1. Abbreviations : MFS Marfan syndrome, WBC White blood cell count, ALT Glutamate aminotransferase, LDH Lactate dehydrogenase, TBIL Total bilirubin, CR Creatinine, GFR Glomerular filtration rate, SIRI Systemic inflammation response index, NLR Neutrophil-to-lymphocyte ratio, MLR Monocyte-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, SII Systemic immune-inflammation index, SCI Systemic coagulation-inflammation index, EoI in AD Aortic dissection tear involvement ranges, IB in AD Involvement of branches in aortic dissection, MA in AD Involvement of mesenteric arteries, RA in AD Involvement of renal arteries, FLM SS False lumen morphology (spiderweb sign), FLM CS False lumen morphology(crescent sign)