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Fig. 2 | Journal of Cardiothoracic Surgery

Fig. 2

From: Circ_0001786 facilitates gefitinib resistance and malignant progression in non-small cell lung cancer via miR-34b-5p/SRSF1

Fig. 2

circ_0001786 knockdown suppressed cell colony formation and promoted gefitinib sensitivity in Gefitinit-resistant NSCLC cell line. (A) circ_0001786 knockdown efficiency in PC9-GR and HCC827-GR cells was checked by qRT-PCR. (B) Cell viability of transfected cells was detected by CCK8 assay after treatment with the indicated concentration of gefitinib. (C) Cell colony formation ability was detected by colony formation assay after circ_0001786 knockdown in PC9-GR and HCC827-GR cells. (D) Cell apoptosis was measured by flow cytometry after circ_0001786 knockdown PC9-GR and HCC827-GR cells. *P < 0.05, **P < 0.01, ***P <0.001

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